Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14812210 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL14810578 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL29434443 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL2791362 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL16784599 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL14812149 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL14811014 | 0.86 | SLC6A3 (0.51) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL30592016 | 0.83 | F2RL1 (0.49) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL16785349 | 0.80 | KDM4E (0.53) | SLC6A3MEN1KMT2APOLBHTT | |
| SCHEMBL29434375 | 0.80 | KDM4E (0.53) | SLC6A3MEN1KMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123508-A1 | PAR2-modulating compounds and their use | ACADIA PHARMACEUTICALS INC. | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123508-A1 | PAR2-modulating compounds and their use | F2RL1, F2R, F2RL3 | SLC6A3 4323/4885MEN1 1639/4885KMT2A 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.