Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 8/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 8/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400638 | 1.00 | P2RX1 (0.55) | P2RX1KCNMA1TMPRSS4SCN9AP2RX4 | |
| SCHEMBL5382253 | 0.92 | KLKB1 (0.48) | P2RX1KCNMA1TMPRSS4SCN9AP2RX4 | |
| SCHEMBL5382620 | 0.91 | SCN9A (0.47) | P2RX1KCNMA1TMPRSS4SCN9AP2RX4 | |
| SCHEMBL5381063 | 0.89 | KLKB1 (0.44) | P2RX1SCN9ACA12CA1CA2 | |
| SCHEMBL5396786 | 0.88 | P2RX1 (0.43) | P2RX1TMPRSS4SCN9ACA12CA1 | |
| SCHEMBL5376176 | 0.88 | PLAU (0.47) | P2RX1TMPRSS4SCN9ACA12CA1 | |
| SCHEMBL5396728 | 0.88 | PLAU (0.47) | P2RX1TMPRSS4SCN9ACA12CA1 | |
| SCHEMBL5382834 | 0.87 | SCN9A (0.41) | P2RX1SCN9ACA12CA1CA2 | |
| SCHEMBL5390622 | 0.86 | LMNA (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL5376114 | 0.86 | PLAU (0.50) | P2RX1TMPRSS4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |