Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839901 | 0.79 | MAPT (0.42) | ALDH1A1BLMRECQLF2F10 | |
| SCHEMBL1839902 | 0.79 | MAPT (0.42) | ALDH1A1BLMRECQLF2F10 | |
| SCHEMBL12285402 | 0.79 | MAPT (0.42) | ALDH1A1BLMRECQLF2F10 | |
| SCHEMBL4240912 | 0.70 | TDP1 (0.54) | HDAC1HDAC2ALDH1A1BLMRECQL | |
| SCHEMBL13762113 | 0.70 | BLM (0.42) | HDAC1HDAC2ALDH1A1BLMRECQL | |
| SCHEMBL11858221 | 0.70 | TDP1 (0.54) | HDAC1HDAC2ALDH1A1BLMRECQL | |
| SCHEMBL15506230 | 0.70 | BLM (0.42) | HDAC1HDAC2BLMRECQLF2 | |
| SCHEMBL11351433 | 0.70 | BLM (0.42) | HDAC1HDAC2BLMRECQLF2 | |
| SCHEMBL11858226 | 0.70 | TDP1 (0.54) | HDAC1HDAC2ALDH1A1BLMRECQL | |
| SCHEMBL28337358 | 0.70 | TDP1 (0.54) | HDAC1HDAC2ALDH1A1BLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105864-A1 | Methods for inhibiting protein kinases | SCHERING CORPORATION | 2007-05-10 | — | — | US | disclosed |
| US-20070105864-A1 | Methods for inhibiting protein kinases | SCHERING CORPORATION | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105864-A1 | Methods for inhibiting protein kinases | PIM1, PIM2, PIM3 | HDAC1 648/4885HDAC2 785/4885ALDH1A1 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.