Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337358 | 1.00 | TDP1 (0.54) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL4240914 | 1.00 | TDP1 (0.54) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL11858226 | 0.86 | TDP1 (0.54) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL11858221 | 0.86 | TDP1 (0.54) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL3140459 | 0.84 | NFE2L2 (0.61) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL29089429 | 0.84 | NFE2L2 (0.61) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL3140451 | 0.84 | NFE2L2 (0.61) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL2675175 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL2675176 | 0.82 | TDP1 (0.50) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL11115897 | 0.82 | NFE2L2 (0.59) | TDP1TSHRCYP2C19CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942523-B | Benzofuran and benzofuran coumarin derivatives, and preparation method and application thereof | 华东师范大学 | 2023-06-09 | — | — | CN | disclosed |
| EP-2238199-B1 | ADDITIVE MIXTURES FOR STYRENIC POLYMERS | BASF SE (DE) | 2011-08-31 | — | — | EP | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | TDP1 1147/4885TSHR 4769/4885CYP2C19 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.