Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | ERN1 | O75460 | 2/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.57 |
| ▸ | JAK2 | O60674 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | MARK3 | P27448 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248924 | 0.88 | HPGD (0.73) | HPGDMEN1KMT2ARAB9AERN1 | |
| SCHEMBL3227656 | 0.86 | MEN1 (0.63) | HPGDMEN1KMT2ARAB9AERN1 | |
| SCHEMBL7222464 | 0.85 | HPGD (0.78) | HPGDMEN1KMT2ARAB9AERN1 | |
| SCHEMBL3722032 | 0.83 | KMO (0.58) | HPGDMEN1KMT2ARAB9AAOC3 | |
| SCHEMBL28860346 | 0.83 | HPGD (1.00) | HPGDMEN1KMT2ARAB9AERN1 | |
| SCHEMBL8150805 | 0.82 | HPGD (0.76) | HPGDMEN1KMT2ARAB9ATSHR | |
| SCHEMBL2999369 | 0.82 | PHGDH (0.69) | HPGDKMT2ATSHRALDH1A1PHGDH | |
| SCHEMBL13952065 | 0.82 | HPGD (0.65) | HPGDMEN1KMT2ARAB9AERN1 | |
| SCHEMBL5943950 | 0.82 | HPGD (0.72) | HPGDMEN1KMT2ARAB9AERN1 | |
| SCHEMBL13702408 | 0.80 | HPGD (0.62) | HPGDMEN1KMT2ARAB9AERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067836-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |