SCHEMBL14508083

SCHEMBL14508083

CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C/C=C/C=C/c1c(C)nn(-c2ccc(C(=O)O)cc2)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 8/20 0.51
KMT2A Q03164 10/20 0.48
MAPT P10636 8/20 0.48
MEN1 O00255 8/20 0.48
MAPK1 P28482 7/20 0.48
ALDH1A1 P00352 6/20 0.48
HTT P42858 5/20 0.48
NPSR1 Q6W5P4 2/20 0.48
GPR55 Q9Y2T6 2/20 0.48
MDM2 Q00987 1/20 0.48
EP300 Q09472 5/20 0.48
L3MBTL1 Q9Y468 6/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
POLB P06746 5/20 0.46
RECQL P46063 2/20 0.46
PKM P14618 2/20 0.46
OPRK1 P41145 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
MMP14 P50281 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278669 1.00 KAT8 (0.51) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12522409 1.00 KAT8 (0.51) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL13092688 0.96 KAT8 (0.53) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12270482 0.96 KAT8 (0.53) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12522411 0.96 KAT8 (0.53) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12451636 0.92 KAT8 (0.44) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12715277 0.91 MAPT (0.54) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL10036077 0.90 MAPT (0.58) KMT2AMAPTMEN1MAPK1ALDH1A1
SCHEMBL12451617 0.88 KAT8 (0.46) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL3188484 0.86 KAT8 (0.48) KAT8KMT2AMAPTMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217504-B2 Method of imaging EASTMAN KODAK COMPANY (US) 2007-05-15 US disclosed
US-7217504-B2 Method of imaging EASTMAN KODAK COMPANY (US) 2007-05-15 US disclosed