SCHEMBL278669

SCHEMBL278669

CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\C=CC=Cc1c(C)nn(-c2ccc(C(=O)O)cc2)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 8/20 0.51
KMT2A Q03164 10/20 0.48
MAPT P10636 8/20 0.48
MEN1 O00255 8/20 0.48
MAPK1 P28482 7/20 0.48
ALDH1A1 P00352 6/20 0.48
HTT P42858 5/20 0.48
NPSR1 Q6W5P4 2/20 0.48
GPR55 Q9Y2T6 2/20 0.48
MDM2 Q00987 1/20 0.48
EP300 Q09472 5/20 0.48
L3MBTL1 Q9Y468 6/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
POLB P06746 5/20 0.46
RECQL P46063 2/20 0.46
PKM P14618 2/20 0.46
OPRK1 P41145 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
MMP14 P50281 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12522409 1.00 KAT8 (0.51) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL14508083 1.00 KAT8 (0.51) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL13092688 0.96 KAT8 (0.53) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12270482 0.96 KAT8 (0.53) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12522411 0.96 KAT8 (0.53) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12451636 0.92 KAT8 (0.44) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL12715277 0.91 MAPT (0.54) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL10036077 0.90 MAPT (0.58) KMT2AMAPTMEN1MAPK1ALDH1A1
SCHEMBL12451617 0.88 KAT8 (0.46) KAT8KMT2AMAPTMEN1MAPK1
SCHEMBL3188484 0.86 KAT8 (0.48) KAT8KMT2AMAPTMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133665-B2 Silver halide photosensitive material and process of producing black and white image using the same FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-8133665-B2 Silver halide photosensitive material and process of producing black and white image using the same FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-20110070548-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL AND PROCESS OF PRODUCING BLACK AND WHITE IMAGE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-24 US disclosed
US-20110070548-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL AND PROCESS OF PRODUCING BLACK AND WHITE IMAGE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-24 US disclosed
US-7812171-B2 Black pigment, black pigment dispersion and black resin composition comprising the same FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-7812171-B2 Black pigment, black pigment dispersion and black resin composition comprising the same FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-7371512-B2 Silver halide photographic emulsion and silver halide photographic lightsensitive material using the same FUJIFILM CORPORATION (JP) 2008-05-13 US disclosed
US-7371512-B2 Silver halide photographic emulsion and silver halide photographic lightsensitive material using the same FUJIFILM CORPORATION (JP) 2008-05-13 US disclosed
US-7312022-B2 Developing solution contains a heterocyclic compound having three or more heteroatoms which when added, capable of enhancing the sensitivity of the silver halide color photosensitive material; high sensitivity, excellent color image storability FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7312022-B2 Developing solution contains a heterocyclic compound having three or more heteroatoms which when added, capable of enhancing the sensitivity of the silver halide color photosensitive material; high sensitivity, excellent color image storability FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7303863-B2 Silver halide emulsion and silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7303863-B2 Silver halide emulsion and silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7229750-B2 Silver halide emulsion and silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7229750-B2 Silver halide emulsion and silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-7172856-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 US disclosed
US-7172856-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME DYNLL1, HNRNPL, AOX1 KAT8 2983/4885KMT2A 2975/4885MAPT 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.