Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PCNA | P12004 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625573 | 0.83 | EPHX1 (0.48) | EPHX1ALDH1A1MAPTABCB1LMNA | |
| SCHEMBL25262351 | 0.82 | LMNA (0.42) | EPHX1ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL16556409 | 0.80 | EPHX1 (0.48) | EPHX1ALDH1A1MAPTABCB1LMNA | |
| SCHEMBL12448166 | 0.80 | EPHX1 (0.48) | EPHX1ALDH1A1MAPTABCB1LMNA | |
| SCHEMBL12448169 | 0.80 | EPHX1 (0.48) | EPHX1ALDH1A1MAPTABCB1LMNA | |
| SCHEMBL19091394 | 0.80 | CYP2C19 (0.33) | EPHX1ALDH1A1MAPTLMNACYP2C19 | |
| SCHEMBL15592822 | 0.80 | MAPT (0.41) | EPHX1ALDH1A1MAPTABCB1LMNA | |
| SCHEMBL17190633 | 0.79 | KDM4E (0.48) | EPHX1ALDH1A1MAPTABCB1LMNA | |
| SCHEMBL12975369 | 0.78 | LMNA (0.36) | ALDH1A1LMNACYP2C19HIF1AEGFR | |
| SCHEMBL777387 | 0.78 | MAPT (0.59) | EPHX1ALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070108405-A1 | Compositions and methods for delivery of biologically active agents | FH FAULDING & CO., LTD. (AU) | 2007-05-17 | — | — | US | disclosed |