Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MVD | P53602 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882025 | 0.81 | HMGCR (0.58) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL15259178 | 0.81 | HMGCR (0.58) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL14864444 | 0.78 | HMGCR (0.54) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL16882027 | 0.76 | HMGCR (0.52) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL8736083 | 0.76 | HMGCR (0.52) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL599363 | 0.75 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL18376075 | 0.75 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL1286788 | 0.75 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| Meglutol SCHEMBL28443 | 0.74 | HMGCR (1.00) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| Meglutol SCHEMBL8718194 | 0.74 | HMGCR (1.00) | HMGCRCHRM1TBXA2RADRA1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315279-A1 | PRODUCTION OF QUINONE DERIVED COMPOUNDS IN OLEAGINOUS YEAST AND FUNGI | DSM IP ASSETS B.V. (NL) | 2014-10-23 | — | — | US | disclosed |
| US-8633009-B2 | Production of quinone derived compounds in oleaginous yeast and fungi | DSM IP ASSETS B.V. (NL) | 2014-01-21 | — | — | US | disclosed |
| US-7232679-B2 | Isoprenoid production | DSM IP ASSETS B.V. (NL) | 2007-06-19 | — | — | US | disclosed |