Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493309 | 0.87 | ALDH1A1 (0.34) | DPP4DPP7DPP9DPP8ALDH1A1 | |
| SCHEMBL14508557 | 0.86 | CYP2C9 (0.47) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL1245311 | 0.76 | MAOB (0.40) | ALDH1A1CYP2C9 | |
| SCHEMBL15262750 | 0.72 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL4642924 | 0.70 | CYP2C9 (0.46) | DPP4ALDH1A1CYP2C9CYP2C19HIF1A | |
| SCHEMBL4642930 | 0.70 | CYP2C9 (0.46) | DPP4ALDH1A1CYP2C9CYP2C19HIF1A | |
| SCHEMBL15262699 | 0.70 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL14493308 | 0.69 | CYP2C9 (0.45) | CYP2C9CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL4645987 | 0.69 | CYP2C9 (0.45) | DPP4ALDH1A1CYP2C9CYP2C19HIF1A | |
| SCHEMBL4645981 | 0.69 | CYP2C9 (0.34) | DPP4ALDH1A1CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232592-B2 | Compounds having a 4,6-difluoroindan-2,5-diyl group; composition of up to 6 compounds gives good response speed, good electrooptical liquid crystal display, matrix liquid crystal display elements | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-06-19 | — | — | US | disclosed |