Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14508585 | 0.94 | F2 (0.77) | F2PRSS1 | |
| SCHEMBL5483369 | 0.92 | F2 (0.62) | F2PRSS1 | |
| SCHEMBL8292342 | 0.91 | F2 (0.61) | F2PRSS1 | |
| SCHEMBL5480327 | 0.85 | F2 (0.68) | F2PRSS1 | |
| SCHEMBL8292346 | 0.85 | F2 (0.67) | F2PRSS1 | |
| SCHEMBL8292324 | 0.84 | F2 (0.68) | F2PRSS1 | |
| SCHEMBL7371121 | 0.83 | F2 (1.00) | F2PRSS1 | |
| SCHEMBL5477489 | 0.81 | F2 (0.70) | F2 | |
| SCHEMBL7367776 | 0.81 | F2 (0.86) | F2 | |
| SCHEMBL14508582 | 0.80 | F2 (0.58) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099927-A1 | Aminoalkyl-pyrazinones and-pyridones as thrombin inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099927-A1 | Aminoalkyl-pyrazinones and-pyridones as thrombin inhibitors | F2, F12, SERPINC1 | F2 1/4885PRSS1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.