Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 15/20 | 0.56 |
| ▸ | CCR7 | P32248 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12087200 | 0.88 | CXCR2 (0.70) | CXCR2CXCR1CCR7 | |
| SCHEMBL12262735 | 0.88 | CXCR2 (0.70) | CXCR2CXCR1CCR7 | |
| SCHEMBL12086754 | 0.84 | CXCR2 (0.69) | CXCR2CXCR1CCR7 | |
| SCHEMBL12262540 | 0.83 | CXCR2 (0.67) | CXCR2CXCR1CCR7 | |
| SCHEMBL14511523 | 0.83 | CXCR2 (0.79) | CXCR2CXCR1 | |
| SCHEMBL14511603 | 0.82 | CXCR2 (0.58) | CXCR2CXCR1CCR7 | |
| SCHEMBL14511438 | 0.82 | CXCR2 (0.58) | CXCR2CXCR1CCR7 | |
| SCHEMBL12086738 | 0.82 | CXCR2 (0.66) | CXCR2CXCR1 | |
| SCHEMBL14511375 | 0.81 | CXCR2 (0.78) | CXCR2CXCR1CCR7 | |
| SCHEMBL12262877 | 0.77 | CXCR2 (0.75) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381590-B1 | 3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2007-06-20 | — | — | EP | disclosed |