Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511365 | 0.80 | LMNA (0.38) | LMNAL3MBTL1TSHRGAACYP1A2 | |
| SCHEMBL14511394 | 0.78 | LMNA (0.46) | LMNAL3MBTL1TSHRGAACYP1A2 | |
| SCHEMBL14513749 | 0.75 | MAPT (0.52) | LMNAL3MBTL1TSHRALDH1A1MAPT | |
| SCHEMBL14057918 | 0.73 | TSHR (0.47) | LMNAL3MBTL1TSHRGAACYP1A2 | |
| SCHEMBL10567645 | 0.73 | MAPT (0.66) | LMNAL3MBTL1TSHRGAACYP1A2 | |
| SCHEMBL26789539 | 0.73 | NPSR1 (0.59) | LMNAL3MBTL1TSHRGAACYP1A2 | |
| SCHEMBL12883186 | 0.73 | TSHR (0.77) | LMNAL3MBTL1TSHRGAATP53 | |
| SCHEMBL26789536 | 0.72 | LMNA (0.53) | LMNAL3MBTL1TSHRGAACYP1A2 | |
| SCHEMBL28042492 | 0.72 | MEN1 (0.50) | LMNATSHRGAACYP1A2TP53 | |
| SCHEMBL14671037 | 0.71 | TSHR (0.53) | LMNAL3MBTL1TSHRGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070098643-A1 | Oligomers of gadolinium chelates, their applicationascontrast products in magnetic resonance imaging and their synthesis intermediates | GUERBET (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098643-A1 | Oligomers of gadolinium chelates, their applicationascontrast products in magnetic resonance imaging and their synthesis intermediates | MGAT2, MGAT1, MGAT3 | LMNA 1383/4885L3MBTL1 452/4885TSHR 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.