Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 8/20 | 0.42 |
| ▸ | YES1 | P07947 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14511613 | 0.91 | BACE1 (0.49) | SRCKDREPHB4BACE1INSR | |
| SCHEMBL1305489 | 0.77 | IRAK4 (0.72) | MAP3K7IRAK4SRCKDRINSR | |
| SCHEMBL17320249 | 0.73 | IRAK4 (0.58) | MAP3K7IRAK4SRCYES1KDR | |
| SCHEMBL19477046 | 0.70 | EHMT2 (0.66) | KDRBRD4BRD2BRD3EHMT2 | |
| SCHEMBL30367074 | 0.70 | EHMT2 (0.66) | KDRBRD4BRD2BRD3EHMT2 | |
| SCHEMBL25622686 | 0.68 | EHMT2 (0.53) | KDRINSRKMT2ABRD4BRD2 | |
| SCHEMBL352214 | 0.68 | IRAK4 (0.62) | MAP3K7IRAK4KDRBACE1INSR | |
| SCHEMBL4130546 | 0.64 | SRC (0.46) | SRCYES1KDREPHB4ABL1 | |
| SCHEMBL21460553 | 0.64 | MAPT (0.64) | INSRAXLSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL265437 | 0.61 | JAK3 (0.74) | MAP3K7IRAK4SRCYES1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | BTK, SYK, LYN | MAP3K7 36/4885IRAK4 239/4885SRC 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.