Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | CCR4 | P51679 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904843 | 0.82 | CCR2 (0.73) | CCR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL4912717 | 0.82 | CCR2 (0.61) | CCR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL4904763 | 0.76 | CCR2 (0.67) | CCR2MEN1KMT2APIK3CAMTOR | |
| SCHEMBL14006343 | 0.70 | CCR2 (0.55) | CCR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL4913044 | 0.70 | CCR2 (0.69) | CCR2CCR4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4907421 | 0.70 | CCR2 (0.57) | CCR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL4935740 | 0.69 | CCR2 (0.67) | CCR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL4913288 | 0.69 | CCR2 (0.69) | CCR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL4909963 | 0.69 | CCR2 (0.58) | CCR2MEN1KMT2ALMNACCR4 | |
| SCHEMBL4907638 | 0.69 | CCR2 (0.66) | CCR2MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067875-A2 | PYRIDINYL SULFONAMIDE MODULATORS OF CHEMOKINE RECEPTORS | GLAXO GROUP LIMTED (GB) | 2007-06-14 | — | — | WO | disclosed |