Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74169 | 0.85 | SLC6A2 (0.47) | IFNAR1SLC6A4SLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL11630699 | 0.83 | IFNAR1 (0.68) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL12728085 | 0.81 | SLC6A4 (0.68) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| Hydrochloric Acid SCHEMBL11635394 | 0.81 | IFNAR1 (0.66) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL11753290 | 0.81 | SLC6A4 (0.69) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL1399400 | 0.80 | IFNAR1 (0.58) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL752552 | 0.79 | IFNAR1 (0.58) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL3400989 | 0.79 | SLC6A4 (0.50) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL30996076 | 0.79 | IFNAR1 (1.00) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL27635780 | 0.79 | KMT2A (0.61) | IFNAR1SLC6A4SLC6A2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117154-A1 | Cyclic lactams comprising three amino acids and a tether chain to control the overall shape of the macromolecule; beta-turn mimetics to explore conformationally restricted structures; proteolytic enzyme resistance (nonhydrolyzing); cell penetration; anticoagulants; anticarcinogenic agents | MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED (IE) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117154-A1 | Cyclic lactams comprising three amino acids and a tether chain to control the overall shape of the macromolecule; beta-turn mimetics to explore conformationally restricted structures; proteolytic enzyme resistance (nonhydrolyzing); cell penetration; anticoagulants; anticarcinogenic agents | F2, BCAT1, DAO | IFNAR1 2766/4885SLC6A4 4470/4885SLC6A2 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.