BCAT1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3240485	0.62	20/20
SCHEMBL3240477	0.60	20/20
SCHEMBL3264126	0.60	20/20
SCHEMBL2841420	0.54	20/20
SCHEMBL3237995	0.53	20/20
SCHEMBL2833852	0.52	20/20
SCHEMBL2841636	0.52	20/20
SCHEMBL2833147	0.52	20/20
SCHEMBL1574611	0.50	20/20
SCHEMBL1574612	0.50	20/20
SCHEMBL1574614	0.50	20/20
SCHEMBL1573401	0.58	19/20
SCHEMBL4572165	0.54	19/20
SCHEMBL2832656	0.53	19/20
SCHEMBL2832658	0.53	19/20
SCHEMBL2832659	0.53	19/20
SCHEMBL2841434	0.51	19/20
SCHEMBL2841437	0.51	19/20
SCHEMBL2841440	0.51	19/20
SCHEMBL1573699	0.50	19/20

Clinical trials — most relevant to BCAT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Role of BCAA in Glucose Homeostasis	PHASE4	UNKNOWN
Treatment of Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C	PHASE3	ACTIVE_NOT_RECRUITING
A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA	PHASE1/PHASE2	WITHDRAWN
Branched-chain Amino Acid Supplementation for Hepatocellular Carcinoma	PHASE2	WITHDRAWN
Investigation of an Amino Acid Supplement on Glucose Levels in Obese Subjects	nan	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects	nan	COMPLETED
How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses	nan	RECRUITING
Alternations in Body Composition of Tonsillectomy Patients During the Recovery Period	nan	UNKNOWN
Plasma Free Amino Acids in Patients With Hepatic Encephalopathy	nan	UNKNOWN
Leucine Requirements in School-Age Children	nan	NOT_YET_RECRUITING
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure	nan	UNKNOWN
Effect of BCAA Supplementation on Muscle Mass, Muscle Quality and Molecular Markers of Muscle Regeneration in CLD Patients	nan	COMPLETED
Alternative Substrates in the Critically Ill Subject	nan	COMPLETED
Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation	nan	COMPLETED
The Effects of Sodium Phenylbutyrate on Circulating Branched Chain Amino Acids	nan	COMPLETED
Lysine Requirement of Elderly Men and Women Over 60 Years of Age	nan	COMPLETED
Resistance Exercise Program and Branched Chain Amino Acid Supplementation in Heart Failure Patients	nan	COMPLETED
Leucine Requirements During Pregnancy	nan	RECRUITING
Branched Chained Amino Acid Supplement in Patients Undergoing Lower Limb Bone Cancer Curettage for Bone Metastasis	nan	NOT_YET_RECRUITING
Effect of Increased Physical Activity and Stopping Evening Snacking in Metabolic Health in Youth With Prediabetes	nan	RECRUITING
Impact of Branched-chain Amino Acids in the Development of Insulin Resistance	nan	COMPLETED
Comparison of Different Weight Loss Diets With Different Protein Content	nan	COMPLETED
Metabolism of Branched-chain Amino Acids in Monocyte/Macrophage During Sepsis	nan	UNKNOWN
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Metabolomics and Bariatric Surgery in Patients With Metabolically Unhealthy Obesity	nan	COMPLETED
Effects of Branch Chain Amino Acids on Glucose Tolerance in Obese Pre-Diabetic Subjects	nan	COMPLETED
Evaluation of Amino Acids Bioavailability in a Food Product Based on a Vegetable Protein Combination	nan	COMPLETED
Determining the Effect of Protein Quality on Post-exercise Anabolism in Active Youth	nan	UNKNOWN
Effect of Branched-chain Amino Acid Supplementation on Muscle Damage	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a BCAT1 binder may also engage these)

Protein	Name	Similarity
P24288	—	0.995	P24288 →
Q9GKM4	—	0.993	Q9GKM4 →
P54690	—	0.967	P54690 →
Q9M401	—	0.959	Q9M401 →
K7QHS5	—	0.956	K7QHS5 →
Q9FYA6	—	0.956	Q9FYA6 →
O35854	—	0.954	O35854 →
BCAT2	Branched-chain-amino-acid aminotransferase, mitochondrial	0.951	landscape →
Q5EA40	—	0.951	Q5EA40 →
O35855	—	0.948	O35855 →
Q5RFI8	—	0.948	Q5RFI8 →
P27119	—	0.945	P27119 →
Q9I8S4	—	0.945	Q9I8S4 →
Q5REP0	—	0.945	Q5REP0 →
B4G0F3	—	0.944	B4G0F3 →
K7QKH1	—	0.942	K7QKH1 →
Q6AY30	—	0.942	Q6AY30 →
Q9D020	—	0.941	Q9D020 →
P27117	—	0.941	P27117 →
E0CSI1	—	0.941	E0CSI1 →
Q7SYN4	—	0.941	Q7SYN4 →
Q3T067	—	0.941	Q3T067 →
P46416	—	0.941	P46416 →
Q9M439	—	0.940	Q9M439 →
Q9H0P0	—	0.940	Q9H0P0 →
P27118	—	0.940	P27118 →
PGM2	Phosphopentomutase	0.940	landscape →
P14019	—	0.939	P14019 →
Q8R127	—	0.939	Q8R127 →
Q7TSV4	—	0.939	Q7TSV4 →