Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | AGER | Q15109 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664193 | 0.83 | PARP1 (0.51) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL3880000 | 0.82 | KDM4E (0.59) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL5252687 | 0.82 | KDM4E (0.59) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL25718894 | 0.81 | KDM4E (0.53) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL3931891 | 0.81 | NAPRT (0.58) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL123202 | 0.81 | KDM4E (0.57) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL2782918 | 0.81 | KDM4E (0.62) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL242926 | 0.81 | SMN1; SMN2 (0.58) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL188175 | 0.81 | NAPRT (0.58) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL2300950 | 0.81 | NAPRT (0.58) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798230-A1 | Substituted alkylamine derivatives and methods of use | Amgen Inc. (US) | 2007-06-20 | — | — | EP | disclosed |