Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 4/20 | 0.42 |
| ▸ | CPT2 | P23786 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637475 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1LMNAGAASIGMAR1 | |
| SCHEMBL5640189 | 0.80 | GAA (0.44) | GAAKMT2AL3MBTL1 | |
| SCHEMBL5638007 | 0.80 | GAA (0.44) | GAAKMT2AL3MBTL1 | |
| SCHEMBL5640756 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1LMNAGAASIGMAR1 | |
| SCHEMBL5640744 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1LMNAGAASIGMAR1 | |
| SCHEMBL12527914 | 0.77 | KMT2A (0.55) | KMT2AL3MBTL1MMP1 | |
| SCHEMBL5638640 | 0.77 | NAAA (0.46) | GAA | |
| SCHEMBL5638689 | 0.77 | F2 (0.48) | GAAKMT2AL3MBTL1 | |
| SCHEMBL5639417 | 0.77 | F2 (0.43) | GAAKMT2AL3MBTL1 | |
| SCHEMBL5637243 | 0.76 | F2 (0.43) | ALDH1A1GAAKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220856-B2 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |
| US-7220856-B2 | Substituted quinoline CCR5 receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-22 | — | — | US | disclosed |