Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566201 | 0.92 | KDM4E (0.43) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| SCHEMBL7499469 | 0.91 | TOP1 (0.41) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| SCHEMBL5279980 | 0.91 | KDM4E (0.40) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL7506073 | 0.91 | KDM4E (0.44) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| SCHEMBL8601235 | 0.91 | SCN5A (0.42) | SCN5AKCNH2LMNAALDH1A1POLB | |
| SCHEMBL8562588 | 0.90 | ALDH1A1 (0.46) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| SCHEMBL8566850 | 0.90 | ALDH1A1 (0.46) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL7502813 | 0.90 | KDM4E (0.39) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL7553048 | 0.90 | SCN5A (0.42) | SCN5AKCNH2HPGDHSD17B10LMNA | |
| SCHEMBL7499390 | 0.89 | SCN5A (0.45) | SCN5AKCNH2LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229996-B2 | Rifamycin derivatives | CUMBRE PHARMACEUTICALS INC. (US) | 2007-06-12 | — | — | US | disclosed |