Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803133 | 0.83 | F2 (0.61) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL21317576 | 0.79 | F2 (0.57) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL16140087 | 0.76 | F2 (0.53) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL1929354 | 0.74 | F2 (0.52) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL2047218 | 0.74 | RAPGEF4 (0.67) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL21117641 | 0.74 | CA1 (0.56) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL4249547 | 0.73 | CA1 (0.50) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL8271353 | 0.72 | CA1 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL330754 | 0.72 | CA1 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL28872882 | 0.71 | RAPGEF4 (0.47) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229480-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-12 | — | — | US | disclosed |