Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14517172 | 0.92 | FAP (0.39) | FAPPTGS1KDM4ELMNAUSP2 | |
| SCHEMBL14517162 | 0.91 | FAP (0.40) | FAPPTGS1KDM4ELMNAUSP2 | |
| SCHEMBL14517148 | 0.91 | FAP (0.38) | FAPPTGS1KDM4ELMNAUSP2 | |
| SCHEMBL14517164 | 0.91 | FAP (0.40) | FAPPTGS1KDM4ELMNAELANE | |
| SCHEMBL14517150 | 0.90 | FAP (0.39) | FAPPTGS1KDM4ELMNA | |
| SCHEMBL14517170 | 0.90 | FAP (0.37) | FAPPTGS1KDM4ELMNAUSP2 | |
| SCHEMBL14517161 | 0.87 | FAP (0.39) | FAPPTGS1KDM4ELMNAELANE | |
| SCHEMBL14517173 | 0.86 | FAP (0.37) | FAPPTGS1KDM4ELMNA | |
| SCHEMBL14517141 | 0.85 | FAP (0.39) | FAPPTGS1KDM4ELMNAUSP2 | |
| SCHEMBL14517115 | 0.85 | FAP (0.39) | FAPPTGS1KDM4ELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205291-B2 | High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |