Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 0.88 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823245 | 0.94 | ADORA2B (1.00) | ADORA2BADORA1 | |
| Hydrochloric Acid SCHEMBL1568738 | 0.93 | ADORA2B (1.00) | ADORA2BADORA1 | |
| SCHEMBL1568723 | 0.91 | ADORA2B (0.80) | ADORA2BADORA1 | |
| SCHEMBL6135851 | 0.91 | ADORA2B (0.79) | ADORA2BADORA1 | |
| SCHEMBL6135922 | 0.87 | ADORA2B (0.76) | ADORA2BADORA1 | |
| SCHEMBL1780802 | 0.87 | ADORA2B (0.72) | ADORA2BADORA1 | |
| SCHEMBL14267711 | 0.85 | ADORA2B (1.00) | ADORA2BADORA1 | |
| SCHEMBL14267682 | 0.84 | ADORA2B (1.00) | ADORA2BADORA1 | |
| SCHEMBL14267676 | 0.84 | ADORA2B (1.00) | ADORA2BADORA1 | |
| SCHEMBL14267702 | 0.84 | ADORA2B (1.00) | ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205403-B2 | 8-Heteroaryl xanthine adenosine A2B receptor antagonists | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2007-04-17 | — | — | US | disclosed |