Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619546 | 0.95 | CRHR1 (0.90) | CRHR1 | |
| SCHEMBL5420927 | 0.93 | CRHR1 (0.86) | CRHR1 | |
| SCHEMBL5410057 | 0.93 | CRHR1 (0.86) | CRHR1 | |
| SCHEMBL5406509 | 0.92 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL6075409 | 0.92 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5444304 | 0.91 | CRHR1 (0.83) | CRHR1 | |
| SCHEMBL5411917 | 0.90 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL5413128 | 0.89 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5423129 | 0.88 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL5409084 | 0.87 | CRHR1 (0.77) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202250-B2 | Substituted arylpyrazines | NEUROGEN CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202250-B2 | Substituted arylpyrazines | NEUROGEN CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |