Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 19/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 18/20 | 0.57 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14500418 | 0.86 | CDK9 (0.60) | CDK9CCNT1TBK1 | |
| SCHEMBL14520938 | 0.85 | CDK9 (0.60) | CDK9CCNT1TBK1 | |
| SCHEMBL14500408 | 0.85 | CDK9 (0.55) | CDK9CCNT1TBK1 | |
| SCHEMBL14500404 | 0.82 | CDK9 (0.52) | CDK9CCNT1TBK1 | |
| SCHEMBL14520456 | 0.82 | CCNT1 (0.54) | CDK9CCNT1TBK1 | |
| SCHEMBL5662450 | 0.81 | CCNT1 (0.55) | CDK9CCNT1TBK1 | |
| SCHEMBL14500413 | 0.81 | CCNT1 (0.57) | CDK9CCNT1TBK1 | |
| SCHEMBL14500292 | 0.81 | CCNT1 (0.57) | CDK9CCNT1TBK1 | |
| SCHEMBL14500365 | 0.81 | CCNT1 (0.60) | CDK9CCNT1TBK1 | |
| SCHEMBL14500378 | 0.80 | CDK9 (0.59) | CDK9CCNT1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |