Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 20/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 19/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659585 | 0.85 | CCNT1 (0.59) | CDK9CCNT1 | |
| Hydrochloric Acid SCHEMBL5662437 | 0.85 | CCNT1 (0.58) | CDK9CCNT1 | |
| SCHEMBL14199808 | 0.75 | CDK9 (0.61) | CDK9CCNT1 | |
| SCHEMBL5663694 | 0.73 | CDK9 (0.68) | CDK9CCNT1 | |
| Hydrochloric Acid SCHEMBL5662221 | 0.72 | CDK9 (0.67) | CDK9CCNT1 | |
| SCHEMBL14500226 | 0.71 | CDK9 (0.48) | CDK9CCNT1 | |
| SCHEMBL14500600 | 0.71 | CDK9 (0.46) | CDK9CCNT1 | |
| Hydrochloric Acid SCHEMBL5661887 | 0.70 | CDK9 (0.46) | CDK9CCNT1 | |
| Hydrochloric Acid SCHEMBL5660244 | 0.70 | CDK9 (0.48) | CDK9CCNT1 | |
| SCHEMBL5662088 | 0.70 | CCNT1 (0.62) | CDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |