Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.91 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471362 | 0.98 | KDM4E (0.87) | KDM4EGAATDP1CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL22440642 | 0.98 | KDM4E (0.87) | KDM4EGAATDP1CYP3A4LMNA | |
| SCHEMBL28507747 | 0.98 | KDM4E (0.87) | KDM4EGAATDP1CYP3A4LMNA | |
| SCHEMBL8159223 | 0.98 | KDM4E (0.87) | KDM4EGAATDP1CYP3A4LMNA | |
| SCHEMBL29096264 | 0.98 | KDM4E (0.87) | KDM4EGAATDP1CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL28961578 | 0.98 | KDM4E (0.87) | KDM4EGAATDP1CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL28961579 | 0.96 | KDM4E (0.83) | KDM4EGAATDP1CYP3A4LMNA | |
| SCHEMBL1217437 | 0.95 | KDM4E (1.00) | KDM4EGAATDP1CYP3A4LMNA | |
| SCHEMBL28516172 | 0.94 | KDM4E (0.80) | KDM4EGAATDP1CYP3A4LMNA | |
| SCHEMBL31114652 | 0.93 | KDM4E (0.95) | KDM4EGAATDP1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1862 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747302-A2 | REPAIR AND OPTIMIZATION OF NANOCOMPOSITE MATERIALS | Nanocore ApS (DK) | 2026-05-27 | — | — | EP | claimed |
| US-20250367650-A1 | IRIDIUM-BASED CATALYST AND PREPARATION METHOD THEREFOR, AND METHOD FOR CATALYZING PROPYLENE HYDROFORMYLATION | NANJING INSTITUTE OF MICROINTERFACE TECH CO LTD (CN) | 2025-12-04 | — | — | US | claimed |
| US-20250361258-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | PRELUDE THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | claimed |
| EP-4321501-B1 | METHOD FOR SYNTHESIZING DIMETHYL 3-(3-OXO-2-PENTYL)CYCLOPENTYLMALONATE AND CATALYST | ZHEJIANG XINHUA CHEMICAL CO LTD (CN) | 2025-10-01 | — | — | EP | claimed |
| CN-120058805-A | Alloy nanocluster and preparation method and application thereof | 清华大学 | 2025-05-30 | — | — | CN | claimed |
| CN-120035598-A | Method for preparing PRMT5 inhibitor | 普莱鲁德疗法股份有限公司 | 2025-05-23 | — | — | CN | claimed |
| EP-4540261-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | Prelude Therapeutics Incorporated (US) | 2025-04-23 | — | — | EP | claimed |
| WO-2025068962-A1 | CATALYST COMPOSITION FOR OLIGOMERIZATION AND A PROCESS FOR ITS PREPARATION | RELIANCE INDUSTRIES LIMITED (IN) | 2025-04-03 | — | — | WO | claimed |
| CN-119555732-A | Method for judging deactivation temperature and deactivation characteristic of hydroformylation catalyst | 万华化学集团股份有限公司 | 2025-03-04 | — | — | CN | claimed |
| US-12233402-B2 | Cross-coupling reaction catalysts, and methods of making and using same | YALE UNIVERSITY (US) | 2025-02-25 | — | — | US | claimed |
| EP-0496393-B1 | Alkylation of azaglycine derivatives | HOECHST AG (DE) | 1995-01-25 | — | — | EP | claimed |
| US-5326875-A | Alkylation of azaglycine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | claimed |
| CN-1023647-C | Novel catalyst composition for olefin/carbon monoxide copolymerization and copolymerization method | SHELL INT RESEARCH (NL) | 1994-02-02 | — | — | CN | claimed |
| EP-0307026-B1 | PROCESS FOR THE PREPARATION OF A BUTENE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-18 | — | — | EP | claimed |
| EP-0259914-B1 | NOVEL CATALYST COMPOSITIONS AND PROCESS FOR OLEFIN/CO COPOLYMERIZATION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-04 | — | — | EP | claimed |
| US-4940787-A | Process for the carbonylation of acetylenic unsaturated compounds | SHELL OIL COMPANY (US) | 1990-07-10 | — | — | US | claimed |
| US-4859764-A | Copolymerization of carbon monoxide and olefin with nitrogen containing phosphine ligand catalyst | SHELL OIL COMPANY (US) | 1989-08-22 | — | — | US | claimed |
| EP-0307026-A1 | Process for the preparation of a butene | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-15 | — | — | EP | claimed |
| EP-0259914-A1 | Novel catalyst compositions and process for olefin/CO copolymerization | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-03-16 | — | — | EP | claimed |
| CN-87105647-A | Novel catalyst composition for olefin/carbon monoxide copolymerization and copolymerization method | — | 1988-03-02 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361258-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | PRMT1, PRMT5, PRMT6 | KDM4E 42/4885GAA 3938/4885TDP1 498/4885 |
| US-12233402-B2 | Cross-coupling reaction catalysts, and methods of making and using same | TET2, TIMCC, MDM4 | KDM4E 515/4885GAA 2325/4885TDP1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.