Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521924 | 0.90 | PTGER4 (0.42) | PTGER4STING1ALDH1A1CYP1A2HTT | |
| SCHEMBL1940860 | 0.88 | BRD4 (0.45) | PTGER4STING1USP2ALDH1A1CYP1A2 | |
| SCHEMBL14521394 | 0.84 | PTGER4 (0.41) | PTGER4ADORA2ASTING1TP53ALDH1A1 | |
| SCHEMBL14521393 | 0.83 | PTGER4 (0.39) | PTGER4STING1USP2ALDH1A1CYP1A2 | |
| SCHEMBL1940913 | 0.80 | STING1 (0.40) | PTGER4STING1USP2ALDH1A1CYP1A2 | |
| SCHEMBL1942913 | 0.78 | GLP1R (0.45) | PTGER4STING1USP2ALDH1A1CYP1A2 | |
| SCHEMBL14521330 | 0.78 | STING1 (0.40) | PTGER4ADORA2ASTING1ALDH1A1ALOX15 | |
| SCHEMBL14521332 | 0.77 | MAPK14 (0.40) | — | |
| SCHEMBL1943217 | 0.77 | PTGER4 (0.44) | PTGER4ADORA2ATP53USP2ALDH1A1 | |
| SCHEMBL1943031 | 0.76 | LMNA (0.46) | PTGER4STING1USP2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |