Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515957 | 0.93 | P2RY12 (0.48) | P2RY12F10FBP1CCR4MEN1 | |
| SCHEMBL14522008 | 0.91 | P2RY12 (0.51) | P2RY12F10FBP1FPR1FPR2 | |
| SCHEMBL5511681 | 0.89 | P2RY12 (0.49) | P2RY12F10FBP1MEN1MAPT | |
| SCHEMBL5508353 | 0.88 | P2RY12 (0.45) | P2RY12F10FBP1CCR4MEN1 | |
| SCHEMBL5511624 | 0.87 | P2RY12 (0.47) | P2RY12F10FBP1CCR4MEN1 | |
| SCHEMBL14522033 | 0.87 | P2RY12 (0.47) | P2RY12F10FBP1CCR4FPR1 | |
| SCHEMBL14522005 | 0.87 | P2RY12 (0.44) | P2RY12F10FBP1MEN1MAPT | |
| SCHEMBL5520241 | 0.87 | P2RY12 (0.58) | P2RY12F10FBP1MEN1MAPT | |
| SCHEMBL14522007 | 0.87 | P2RY12 (0.43) | P2RY12F10FBP1MEN1MAPT | |
| SCHEMBL5511772 | 0.86 | P2RY12 (0.46) | P2RY12F10FBP1CCR4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205296-B2 | Substituted 2H-1,3-benzoxazin-4(3H)-ones | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205296-B2 | Substituted 2H-1,3-benzoxazin-4(3H)-ones | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-04-17 | — | — | US | disclosed |