Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14522007 | 0.97 | P2RY12 (0.43) | P2RY12F10KMT2AMEN1MAPT | |
| SCHEMBL5508353 | 0.92 | P2RY12 (0.45) | P2RY12F10KMT2AMEN1MAPT | |
| SCHEMBL5515957 | 0.90 | P2RY12 (0.48) | P2RY12F10KMT2AMEN1MAPT | |
| SCHEMBL5514509 | 0.89 | P2RY12 (0.46) | P2RY12F10ROCK2KMT2AMEN1 | |
| SCHEMBL14522008 | 0.88 | P2RY12 (0.51) | P2RY12F10FBP1 | |
| SCHEMBL14522016 | 0.87 | P2RY12 (0.48) | P2RY12F10KMT2AMEN1MAPT | |
| SCHEMBL5511681 | 0.86 | P2RY12 (0.49) | P2RY12F10KMT2AMEN1MAPT | |
| SCHEMBL5511772 | 0.86 | P2RY12 (0.46) | P2RY12F10FBP1 | |
| SCHEMBL14544539 | 0.86 | ROCK2 (0.32) | ROCK2ROCK1HRH3MAPK14CDC42BPA | |
| SCHEMBL14522033 | 0.86 | P2RY12 (0.47) | P2RY12F10KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205296-B2 | Substituted 2H-1,3-benzoxazin-4(3H)-ones | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205296-B2 | Substituted 2H-1,3-benzoxazin-4(3H)-ones | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-04-17 | — | — | US | disclosed |