Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524154 | 0.91 | ELANE (0.64) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8344430 | 0.91 | ELANE (0.68) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14524163 | 0.90 | ELANE (0.56) | ELANECYP2C9CYP3A4 | |
| SCHEMBL5205336 | 0.90 | ELANE (0.67) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14523477 | 0.89 | ELANE (0.56) | ELANECYP2C9CYP3A4 | |
| SCHEMBL5202163 | 0.89 | ELANE (0.66) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8342471 | 0.89 | ELANE (0.59) | ELANECYP2C9CYP3A4 | |
| SCHEMBL5201907 | 0.89 | ELANE (0.59) | ELANECYP2C9CYP3A4 | |
| SCHEMBL5201636 | 0.88 | ELANE (0.58) | ELANECYP2C9CYP3A4 | |
| SCHEMBL8344440 | 0.88 | ELANE (0.59) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230017-B2 | Dihydropyridinone derivatives | BAYER HEALTHCARE AG (DE) | 2007-06-12 | — | — | US | disclosed |