Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563224 | 0.85 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7031855 | 0.84 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5701565 | 0.82 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3796581 | 0.81 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7585308 | 0.81 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12095074 | 0.81 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17373026 | 0.79 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL98210 | 0.79 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14525085 | 0.79 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5701640 | 0.79 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7201481-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2007-04-10 | — | — | US | disclosed |