SCHEMBL145249

SCHEMBL145249

CN[C@H]1CCCC[C@@H]1NC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113491 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL30327955 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL145251 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL794147 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL120496 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL428868 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL2745491 1.00 ALDH1A1 (0.32) ALDH1A1HSD17B10KDM4EEPHX1
SCHEMBL24062219 0.96 ALDH1A1 (0.37) ALDH1A1HSD17B10KDM4EEPHX1
Hydrochloric Acid SCHEMBL4083778 0.96 ALDH1A1 (0.30) ALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL31511693 0.96 ALDH1A1 (0.30) ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4629 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4613745-A2 PROCESS FOR PREPARING A COT INHIBITOR COMPOUND Gilead Sciences, Inc. (US) 2025-09-10 EP claimed
EP-4608796-A1 PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-09-03 EP claimed
US-12365666-B2 Process for preparing a Cot inhibitor compound GILEAD SCIENCES, INC. (US) 2025-07-22 US claimed
WO-2025043152-A1 METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-27 WO claimed
CN-119504617-A Preparation method of Perilla Wo Leisheng intermediate 菏泽皓元医药科技有限公司 2025-02-25 CN claimed
WO-2024137495-A9 FOSTEMSAVIR INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF NAVINTA, LLC (US) 2024-07-25 WO claimed
WO-2024137495-A1 FOSTEMSAVIR INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF NAVINTA, LLC (US) 2024-06-27 WO claimed
US-20240208980-A1 Fostemsavir Intermediates and Process for the Preparation Thereof NAVINTA, LLC 2024-06-27 US claimed
US-20240199579-A1 PROCESS FOR PREPARING A COT INHIBITOR COMPOUND GILEAD SCIENCES, INC. 2024-06-20 US claimed
CN-116199633-B Method for preparing revalutamide 甘肃省化工研究院有限责任公司 2024-05-31 CN claimed
US-7919627-B2 Synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine derivatives by protecting the hydroxyl group of (6-chloro-pyridin-3-yl)-methanol, reacting with pyrazole, and reacting with hydroxylamine or a derivative or an oxime ENANTA PHARMACEUTICALS, INC. (US) 2011-04-05 US claimed
US-7884123-B2 3-(1H-indol-2-yl)-1H-thieno[2,3-c]pyrazole-5-(N-phenoxycarboxamide); anticancer agents; protein kinase inhibitors AVENTIS PHARMA S.A. (FR) 2011-02-08 US claimed
EP-2245020-A2 THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF Abbott Laboratories (US) 2010-11-03 EP claimed
EP-1858898-B1 HYDRAZINOCARBONYL-THIENO[2,3-C]PYRAZOLES, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE AVENTIS PHARMA SA (FR) 2009-08-26 EP claimed
WO-2009086163-A2 THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF ABBOTT LABORATORIES (US) 2009-07-09 WO claimed
US-20090163470-A1 THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF ABBOTT LABORATORIES (US) 2009-06-25 US claimed
US-20080058402-A1 Substituted Thieno[2,3-c]pyrazoles, Process for Preparing Them, Compositions Containing Them, and Use Thereof AVENTIS PHARMA S.A. (FR) 2008-03-06 US claimed
US-20060247440-A1 Processes for the preparation of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine ENANTA PHARMACEUTICALS, INC. 2006-11-02 US claimed
EP-1713796-A1 PROCESS FOR PREPARING SUBSTITUTED BENZOPYRAN COMPOUNDS SK CHEMICALS CO., LTD. (KR) 2006-10-25 EP claimed
WO-2005077942-A1 PROCESS FOR PREPARING SUBSTITUTED BENZOPYRAN COMPOUNDS SK CHEMICALS, CO., LTD. (KR) 2005-08-25 WO claimed