Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432603 | 1.00 | F10 (0.51) | F10F2HDAC4HDAC6SMN1; SMN2 | |
| SCHEMBL5432602 | 1.00 | F10 (0.51) | F10F2HDAC4HDAC6SMN1; SMN2 | |
| SCHEMBL13461888 | 0.78 | F10 (0.55) | F10F2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4691317 | 0.77 | F10 (0.54) | F10F2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8305363 | 0.77 | F10 (0.54) | F10F2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8354818 | 0.77 | F10 (0.54) | F10F2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31467437 | 0.77 | TSHR (0.72) | HDAC4HDAC6SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24062392 | 0.77 | BTK (0.57) | HDAC4HDAC6KMT2AGAAL3MBTL1 | |
| SCHEMBL12649367 | 0.77 | BTK (0.57) | HDAC4HDAC6KMT2AGAAL3MBTL1 | |
| SCHEMBL16099696 | 0.77 | BTK (0.57) | HDAC4HDAC6KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | disclosed |