Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691317 | 1.00 | F10 (0.54) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL8354818 | 1.00 | F10 (0.54) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL13461888 | 0.84 | F10 (0.55) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL4691316 | 0.83 | F10 (0.52) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL8310682 | 0.77 | RAB9A (0.70) | F10SMN1; SMN2MEN1GAAHTT | |
| SCHEMBL14524982 | 0.77 | F10 (0.51) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL5432602 | 0.77 | F10 (0.51) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL5432603 | 0.77 | F10 (0.51) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL8259245 | 0.75 | F10 (0.55) | F10F2SMN1; SMN2MEN1GAA | |
| SCHEMBL17017323 | 0.72 | HCRTR1 (0.55) | F10MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |