Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632216 | 0.83 | KDM4E (0.44) | RAB9AALDH1A1 | |
| SCHEMBL13547615 | 0.83 | SMN1; SMN2 (0.38) | RAB9ANPC1P2RX7HPGDGRM5 | |
| SCHEMBL14525218 | 0.81 | KIT (0.40) | POLBP2RX7CNR2 | |
| SCHEMBL25690322 | 0.81 | BRD4 (0.44) | BRD4RAB9ANPC1CNR1POLB | |
| SCHEMBL27398469 | 0.78 | SCN10A (0.46) | BRD4RAB9ANPC1CNR1POLB | |
| SCHEMBL25690235 | 0.78 | BRD4 (0.41) | BRD4RAB9ANPC1CNR1POLB | |
| SCHEMBL21762134 | 0.75 | P2RX7 (0.45) | BRD4RAB9ANPC1CNR1POLB | |
| SCHEMBL25690219 | 0.74 | PTPN1 (0.42) | BRD4RAB9ANPC1CNR1POLB | |
| SCHEMBL27398471 | 0.74 | PARP1 (0.41) | BRD4RAB9ANPC1CNR1POLB | |
| SCHEMBL8300009 | 0.73 | P2RX7 (0.70) | BRD4RAB9ANPC1CNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208603-B2 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2007-04-24 | — | — | US | disclosed |
| US-7208603-B2 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2007-04-24 | — | — | US | disclosed |