Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525862 | 0.84 | CA12 (0.51) | BCHEGSK3BCDK5CDK5R1MAPK13 | |
| SCHEMBL29751906 | 0.84 | CA12 (0.49) | DHFRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL16814673 | 0.84 | CA12 (0.49) | DHFRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL14228010 | 0.83 | L3MBTL1 (0.44) | MAPK14DHFRKDM4EALDH1A1MAPT | |
| SCHEMBL3925327 | 0.82 | CA12 (0.51) | DHFRENPP3ENPP1CA12CA1 | |
| SCHEMBL9612925 | 0.81 | MAPT (0.53) | BCHEMAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL9613128 | 0.81 | TNF (0.43) | BCHEMAPK11MAPK14KDM4EALDH1A1 | |
| SCHEMBL24662849 | 0.81 | BCHE (0.50) | BCHEGSK3BCDK5CDK5R1DHFR | |
| SCHEMBL14461161 | 0.81 | MAPT (0.55) | BCHEMAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL9612929 | 0.81 | KDM4E (0.51) | DHFRKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070080628-A1 | Electroluminescent devices comprising 2-(p-triphenyl)-3-phenyl-pyrazine derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2007-04-12 | — | — | US | disclosed |
| US-20070080628-A1 | Electroluminescent devices comprising 2-(p-triphenyl)-3-phenyl-pyrazine derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2007-04-12 | — | — | US | disclosed |
| EP-1687856-B1 | ELECTROLUMINESCENT DEVICES COMPRISING 2-(P-TRIPHENYL)-3-PHENYL-PYRAZINE DERIVATIVES | CIBA SC HOLDING AG (CH) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070080628-A1 | Electroluminescent devices comprising 2-(p-triphenyl)-3-phenyl-pyrazine derivatives | C1S, TYR, C5 | BCHE 3214/4885GSK3B 4766/4885CDK5 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.