Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525847 | 1.00 | HTR1D (0.40) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL14526572 | 0.91 | DRD2 (0.38) | HTR1DHTR1BDRD2DRD3HTR1A | |
| SCHEMBL14228685 | 0.91 | HTR1D (0.38) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL1142357 | 0.89 | TLR4 (0.36) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL18137089 | 0.88 | HTR1D (0.34) | HTR1DHTR1BDRD2DRD3 | |
| SCHEMBL14526555 | 0.88 | TLR4 (0.36) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL14525717 | 0.88 | HTR1D (0.39) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL14526576 | 0.88 | TLR4 (0.36) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL14526584 | 0.86 | HTR1D (0.35) | HTR1DHTR1BTLR4DRD2DRD3 | |
| SCHEMBL14526560 | 0.86 | HTR1D (0.35) | HTR1DHTR1BTLR4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7198827-B1 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-7198827-B1 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-04-03 | — | — | US | disclosed |