Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.56 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447781 | 0.82 | NOTUM (0.78) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL6887590 | 0.74 | ALDH1A1 (0.71) | CHKAALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL21792324 | 0.73 | NOTUM (1.00) | NOTUMKEAP1CYP1A2CYP2C19 | |
| SCHEMBL21792282 | 0.73 | NOTUM (1.00) | NOTUMKEAP1CYP1A2CYP2C19 | |
| SCHEMBL482167 | 0.72 | NOTUM (0.64) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL21777006 | 0.72 | NOTUM (1.00) | NOTUMKMT2ACYP19A1KEAP1 | |
| SCHEMBL11102521 | 0.72 | NOTUM (1.00) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL76794 | 0.72 | NOTUM (0.64) | NOTUMMAPTCYP19A1KEAP1LMNA | |
| SCHEMBL8117312 | 0.72 | NOTUM (0.64) | NOTUMCYP19A1KEAP1 | |
| SCHEMBL1186707 | 0.72 | NOTUM (0.64) | NOTUMMAPTCYP19A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202254-B2 | Antibacterial compounds: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-04-10 | — | — | US | disclosed |