Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219138 | 1.00 | CRBN (0.38) | CRBNUSP2ITGB3ITGB2ITGB1 | |
| SCHEMBL23182639 | 1.00 | CRBN (0.38) | CRBNUSP2ITGB3ITGB2ITGB1 | |
| SCHEMBL5324369 | 0.84 | — | — | |
| SCHEMBL12562520 | 0.84 | — | — | |
| Dihydroorotate SCHEMBL29901858 | 0.81 | CAD (0.43) | CRBNITGB3ITGB2ITGB1ITGAV | |
| Dihydroorotate SCHEMBL417324 | 0.81 | CAD (0.43) | CRBNITGB3ITGB2ITGB1ITGAV | |
| Dihydroorotate SCHEMBL121953 | 0.81 | CAD (0.43) | CRBNITGB3ITGB2ITGB1ITGAV | |
| Dihydroorotate SCHEMBL758070 | 0.81 | CAD (0.43) | CRBNITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL6652022 | 0.79 | MEN1 (0.38) | CRBNITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL24491564 | 0.79 | RGS12 (0.31) | CRBNTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790636-A1 | PIPERIDINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-05-30 | — | — | EP | disclosed |