Sugi Predict

Sugi Predict / Targets / CAD

CAD

Multifunctional protein CAD · P27708 · CAD on Sugi Atlas →

589 patent compounds predicted against CAD, 153 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL10479155 SCHEMBL10479155 0.64 2/20
SCHEMBL10479392 SCHEMBL10479392 0.64 2/20
SCHEMBL23260109 SCHEMBL23260109 0.40 2/20
SCHEMBL24928556 SCHEMBL24928556 0.40 2/20
SCHEMBL25043983 SCHEMBL25043983 0.40 2/20
SCHEMBL17962532 SCHEMBL17962532 0.37 2/20
Procysteine Procysteine (SCHEMBL9139321) 0.36 2/20
Procysteine Procysteine (SCHEMBL4164380) 0.35 2/20
Procysteine Procysteine (SCHEMBL8428864) 0.35 2/20
Procysteine Procysteine (SCHEMBL10623235) 0.35 2/20
SCHEMBL1973599 SCHEMBL1973599 0.34 2/20
SCHEMBL5550440 SCHEMBL5550440 0.34 2/20
SCHEMBL9487701 SCHEMBL9487701 0.33 2/20
SCHEMBL10949228 SCHEMBL10949228 0.33 2/20
SCHEMBL18576561 SCHEMBL18576561 0.33 2/20
SCHEMBL9362483 SCHEMBL9362483 0.31 2/20
SCHEMBL18109136 SCHEMBL18109136 1.00 1/20
SCHEMBL18109137 SCHEMBL18109137 1.00 1/20
SCHEMBL18109139 SCHEMBL18109139 1.00 1/20
SCHEMBL15865950 SCHEMBL15865950 0.62 1/20

Clinical trials — most relevant to CAD by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
PERIODONTAL HEALTH IN PATIENTS ACUTELY ADMITTED FOR MYOCARDIAL INFARCTION: A CASE CONTROL STUDY nanRECRUITING
The Spanish Familial Hypercholesterolaemia Cohort Study nanRECRUITING
NLR AND CRP Useful as Cost-Effective Preliminary Prognostic Markers in ST-Elevation Myocardial Infarction nanRECRUITING
Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making nanWITHDRAWN
Frequency of Metabolic Dysfunction Associated Fatty Liver Disease in Patients With Acute Coronary Syndromes nanNOT_YET_RECRUITING
The Precision CAD Trial nanACTIVE_NOT_RECRUITING
Genetic Predisposition of Coronary Artery Disease -- The COROGENE-Study nanUNKNOWN
Multi-Analyte, Genetic, and Thrombogenic Markers of Atherosclerosis nanUNKNOWN
Homocysteine and Coronary Artery Disease nanCOMPLETED
Clinical Features, Current Treatment and Clinical Outcomes in Patients With INR-CAD: a Cohort Study nanRECRUITING
Combined Use of Multiple Biomarkers With Stress Testing to Detect Coronary Artery Disease nanCOMPLETED
The Genetics and Vascular Health Check Study (GENVASC) Aims to Help Determine Whether Gathering Genetic Information Can Improve the Prediction of Risk of Coronary Artery Disease (CAD) nanRECRUITING
Comparative of Plasma Proteomics & Metabolomics in Coronary Artery Disease: Obstructive,Non-Obstructive, & No Lesions nanRECRUITING
Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease nanCOMPLETED
Artificial Intelligence for Preventing Heart Disease (AiPHD): Observational, Single Center, Prospective and Retrospective Study nanCOMPLETED
Myocardial Ischemia in Non-obstructive Coronary Artery Disease nanCOMPLETED
Bempedoic Acid in PPCI Impact on Clinical Outcome and Inflammatory Markers nanNOT_YET_RECRUITING
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Interplay of miRNA-146a and miRNA-126 in Chronic Periodontitis Patients With Coronary Artery Disease nanCOMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Molecular & Clinical Evaluation of Low HDL Syndromes nanCOMPLETED
Multi-omics Study of Young Adults Coronary Syndrome Patients nanUNKNOWN
Arterial Composition and Cardiovascular Outcome in DIabeteS nanUNKNOWN
Nosocomial Pneumonia After Coronary Artery Bypass Grafting nanRECRUITING
Genetics of CRP in Families With Myocardial Infarction nanCOMPLETED
Clinical Effect of No-touch Harvesting Technique in OPCABG nanUNKNOWN
Prediction of Coronary Artery Disease Based on Multimodal, Non-contact Information With Artificial Intelligence nanCOMPLETED
Effects of Curcumin on Markers of Cardiovascular Risk in Patients With CAD nanWITHDRAWN
Blood Factors and Peripheral Arterial Disease Outcomes nanCOMPLETED
Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a CAD binder may also engage these)

ProteinNameSimilarity
P08955 — 1.000 P08955 →
B2RQC6 — 1.000 B2RQC6 →
Q75D66 — 0.999 Q75D66 →
O94313 — 0.998 O94313 →
P05990 — 0.998 P05990 →
Q8C196 — 0.998 Q8C196 →
P07756 — 0.997 P07756 →
P46056 — 0.996 P46056 →
Q91437 — 0.996 Q91437 →
O93937 — 0.995 O93937 →
Q18990 — 0.995 Q18990 →
Q7S8A6 — 0.994 Q7S8A6 →
Q887L5 — 0.993 Q887L5 →
CPS1 Carbamoyl-phosphate synthase [ammonia], mitochondrial 0.992 landscape →
Q4K416 — 0.992 Q4K416 →
P07259 — 0.992 P07259 →
P0CN04 — 0.992 P0CN04 →
B9KHF1 — 0.992 B9KHF1 →
Q8TG24 — 0.992 Q8TG24 →
O85347 — 0.992 O85347 →
P38095 — 0.992 P38095 →
Q7N199 — 0.991 Q7N199 →
A8GIR9 — 0.991 A8GIR9 →
B4F0N7 — 0.991 B4F0N7 →
B0JU82 — 0.991 B0JU82 →
Q0T0Z5 — 0.991 Q0T0Z5 →
P18185 — 0.991 P18185 →
B2U0S0 — 0.991 B2U0S0 →
Q5BBV9 — 0.991 Q5BBV9 →
P0A2I5 — 0.991 P0A2I5 →