Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.47 |
| ▸ | HEXB | P07686 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297981 | 0.96 | HEXA (0.48) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL13297979 | 0.92 | FTO (0.49) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL13297957 | 0.89 | HEXA (0.52) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL3297122 | 0.87 | HDAC3 (0.52) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL13297944 | 0.86 | HEXA (0.55) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL3296718 | 0.86 | HDAC3 (0.50) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL13297975 | 0.85 | HEXA (0.49) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL3302098 | 0.84 | HEXA (0.47) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL13297973 | 0.84 | HEXA (0.48) | HEXAHEXBFTOCYP2D6POLB | |
| SCHEMBL3300095 | 0.84 | FTO (0.49) | HEXAHEXBFTOCYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787985-A1 | Azonafide derivatives, methods for their production and pharmaceutical compositions therefrom | Unibioscreen S.A. (BE) | 2007-05-23 | — | — | EP | disclosed |
| WO-2007054292-A2 | AZONAFIDE DERIVATIVES, METHODS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THEREFROM | UNIBIOSCREEN S.A. (BE) | 2007-05-18 | — | — | WO | disclosed |