Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 13/20 | 0.52 |
| ▸ | CHUK | O15111 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040242 | 0.87 | IKBKB (0.49) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL5035290 | 0.80 | IKBKB (0.52) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL4590194 | 0.80 | IKBKB (0.46) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL4590044 | 0.80 | IKBKB (0.46) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL4595720 | 0.80 | IKBKB (0.45) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL5034346 | 0.76 | IKBKB (0.44) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL4589931 | 0.72 | IKBKB (0.62) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL4590195 | 0.72 | IKBKB (0.73) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL552099 | 0.71 | IKBKB (0.72) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL552552 | 0.70 | IKBKB (0.67) | IKBKBCHUKAURKAFLT3CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062318-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |