⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19192554 | 0.74 | — | — | |
| SCHEMBL18789081 | 0.74 | — | — | |
| SCHEMBL23026401 | 0.72 | — | — | |
| SCHEMBL18780120 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL27570570 | 0.71 | — | — | |
| SCHEMBL18569616 | 0.71 | — | — | |
| SCHEMBL5439770 | 0.69 | — | — | |
| SCHEMBL5439775 | 0.69 | — | — | |
| SCHEMBL23652660 | 0.69 | — | — | |
| SCHEMBL18684039 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-10859578-B2 | Fluorescent methods and materials for directed biomarker signal amplification | SKIGEN, INC. (US) | 2020-12-08 | — | — | US | disclosed |
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |
| US-20190033317-A1 | Fluorescent Methods and Materials for Directed Biomarker Signal Amplification | SIRIGEN, INC. | 2019-01-31 | — | — | US | disclosed |