Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249292 | 0.91 | GP6 (0.51) | PTGER4CCR2RHEBAGTR1AGTR2 | |
| SCHEMBL1249443 | 0.91 | CYP19A1 (0.53) | PTGER4CCR2RHEBAGTR1AGTR2 | |
| SCHEMBL1250283 | 0.90 | RPA1 (0.50) | PTGER4CCR2RHEBMEN1ALDH1A1 | |
| SCHEMBL12914988 | 0.90 | PTGER4 (0.52) | PTGER4CCR2RHEBAGTR1AGTR2 | |
| SCHEMBL14529390 | 0.89 | PTGER4 (0.48) | PTGER4CCR2RHEBMEN1ALDH1A1 | |
| SCHEMBL1247955 | 0.89 | PTGER4 (0.49) | PTGER4CCR2RHEBAGTR1AGTR2 | |
| SCHEMBL1249282 | 0.89 | PTGER4 (0.49) | PTGER4CCR2RHEBAGTR1AGTR2 | |
| SCHEMBL1250212 | 0.89 | PTGER4 (0.49) | PTGER4CCR2AGTR1AGTR2MEN1 | |
| SCHEMBL1250111 | 0.89 | PTGER4 (0.54) | PTGER4CCR2AGTR1AGTR2ALDH1A1 | |
| SCHEMBL1250584 | 0.88 | NPC1 (0.52) | PTGER4CCR2AGTR1AGTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429763-B1 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-05-30 | — | — | EP | disclosed |