Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270446 | 0.90 | NTRK1 (0.42) | NTRK1SCD5HCRTR1HCRTR2NPC1 | |
| SCHEMBL5271916 | 0.90 | NTRK1 (0.42) | NTRK1SCD5HCRTR1HCRTR2NPC1 | |
| SCHEMBL14529197 | 0.88 | KDM4E (0.44) | NTRK1SCD5HCRTR1GRM5 | |
| SCHEMBL13213189 | 0.82 | NTRK1 (0.41) | NTRK1SCD5 | |
| SCHEMBL14529778 | 0.81 | ADORA2A (0.43) | NTRK1ADORA2A | |
| SCHEMBL5268570 | 0.81 | ADORA2A (0.44) | NTRK1SCD5HCRTR1HCRTR2NPC1 | |
| SCHEMBL5267292 | 0.81 | KDM5A (0.34) | NTRK1SCD5HCRTR1NPC1RAB9A | |
| SCHEMBL14529496 | 0.80 | ALDH1A1 (0.45) | NTRK1SCD5NPC1RAB9A | |
| SCHEMBL14529775 | 0.80 | KCNJ6 (0.36) | NTRK1HCRTR1HCRTR2 | |
| SCHEMBL5269213 | 0.79 | GRM5 (0.35) | NTRK1SCD5HCRTR1HCRTR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |