SCHEMBL14529645

SCHEMBL14529645

O=C1C2CCCCC1CN(Cc1ccccc1)C2

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
FUCA1 P04066 2/20 0.51
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
S1PR1 P21453 1/20 0.49
S1PR5 Q9H228 1/20 0.49
SIGMAR1 Q99720 1/20 0.48
ACHE P22303 1/20 0.47
OPRL1 P41146 1/20 0.47
CCR3 P51677 1/20 0.46
CYP19A1 P11511 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852290 0.96 FUCA1 (0.51) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL21220647 0.96 FUCA1 (0.51) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL21238086 0.96 FUCA1 (0.51) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL17560348 0.93 FUCA1 (0.55) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL30875889 0.93 FUCA1 (0.55) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL20417932 0.93 FUCA1 (0.55) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL19518531 0.93 FUCA1 (0.55) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL1514852 0.93 FUCA1 (0.55) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
Ethylene SCHEMBL2678737 0.89 FUCA1 (0.51) ALDH1A1FUCA1CYP1A2CYP3A4CYP2D6
SCHEMBL2962712 0.89 FUCA1 (0.58) FUCA1S1PR1S1PR5SIGMAR1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007051255-A1 PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING AN AZACYCLIC RING SYSTEM THE UNIVERSITY OF SYDNEY (AU) 2007-05-10 WO disclosed