Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220647 | 1.00 | FUCA1 (0.51) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2852290 | 1.00 | FUCA1 (0.51) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14529645 | 0.96 | ALDH1A1 (0.53) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30875889 | 0.93 | FUCA1 (0.55) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19518531 | 0.93 | FUCA1 (0.55) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20417932 | 0.93 | FUCA1 (0.55) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17560348 | 0.93 | FUCA1 (0.55) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1514852 | 0.93 | FUCA1 (0.55) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| Ethylene SCHEMBL2678737 | 0.89 | FUCA1 (0.51) | FUCA1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2962712 | 0.89 | FUCA1 (0.58) | FUCA1S1PR1S1PR5SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026375-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2019152946-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | ALKERMES, INC. (US) | 2019-08-08 | — | — | WO | disclosed |