Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530411 | 0.89 | TDP1 (0.31) | KDM4EALOX15 | |
| SCHEMBL14021779 | 0.89 | TDP1 (0.35) | KDM4EALOX15 | |
| SCHEMBL14006930 | 0.84 | — | — | |
| SCHEMBL28984184 | 0.81 | CA12 (0.31) | — | |
| SCHEMBL29678119 | 0.81 | CA12 (0.31) | — | |
| SCHEMBL14006932 | 0.77 | — | — | |
| SCHEMBL3676295 | 0.75 | MAPT (0.33) | KDM4EMAPT | |
| SCHEMBL18404605 | 0.74 | ALOX15 (0.50) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL3108814 | 0.74 | KDM4E (0.50) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL14006935 | 0.74 | BLM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053415-A2 | AGENTS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | NOVARTIS VACCINES AND DIAGNOSTICS INC. (US) | 2007-05-10 | — | — | WO | disclosed |