Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2912572 | 0.91 | NPC1 (0.56) | NPC1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL3254682 | 0.91 | TSHR (0.55) | NPC1LMNATSHRSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL6755818 | 0.89 | TSHR (0.53) | NPC1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL17458867 | 0.86 | SMN1; SMN2 (0.51) | NPC1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL6002740 | 0.85 | TSHR (0.50) | NPC1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL6004065 | 0.85 | TSHR (0.50) | NPC1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL33918 | 0.84 | TSHR (0.62) | NPC1LMNATSHRSMN1; SMN2HTT | |
| SCHEMBL144813 | 0.81 | TSHR (0.69) | TSHRSMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL1801455 | 0.81 | NPBWR1 (0.54) | NPC1LMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6243855 | 0.81 | TSHR (0.47) | NPC1LMNATSHRSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142498-B2 | Keratin dyeing compounds, compositions containing them, and method and use thereof | WELLA OPERATIONS US, LLC (US) | 2021-10-12 | — | — | US | claimed |
| US-20200247749-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | WELLA OPERATIONS US, LLC | 2020-08-06 | — | — | US | claimed |
| WO-2019074736-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | NOXELL CORPORATION (US) | 2019-04-18 | — | — | WO | claimed |
| WO-2014202150-A1 | NEW CATIONIC DYES, KITS AND COMPOSITIONS THEREOF, AND PROCESS FOR DYEING KERATIN FIBERS | ALFA PARF GROUP S.P.A. (IT) | 2014-12-24 | — | — | WO | claimed |
| EP-1011619-B2 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2012-07-04 | — | — | EP | claimed |
| EP-1598047-B1 | Composition for coloring of keratin fibres | KPSS KAO GMBH (DE) | 2011-11-30 | — | — | EP | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-7678158-B2 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | THE PROCTER & GAMBLE COMPANY (US) | 2010-03-16 | — | — | US | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | claimed |
| EP-1720615-B1 | COSMETIC HAIR DYEING COMPOSITIONS CONTAINING THEM AND USE THEREOF | PROCTER & GAMBLE (US) | 2009-12-30 | — | — | EP | claimed |
| EP-1011619-A1 | DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 2000-06-28 | — | — | EP | claimed |
| WO-1999011231-A1 | DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 1999-03-11 | — | — | WO | claimed |
| US-5785717-A | Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-07-28 | — | — | US | claimed |
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | claimed |
| EP-0728464-B1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| US-5637115-A | Oxidation hair dye compositions containing developers, couplers, and AZO dyes | WELLA AKTIENGESELLSCHAT (DE) | 1997-06-10 | — | — | US | claimed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | claimed |
| EP-0728464-A1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | claimed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142498-B2 | Keratin dyeing compounds, compositions containing them, and method and use thereof | KRT18, MARK4, MKI67 | NPC1 4813/4885LMNA 981/4885TSHR 3729/4885 |
| US-20200247749-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | KRT18, PRKDC, MKI67 | NPC1 4808/4885LMNA 698/4885TSHR 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.